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Purpose the present investigation is to study the influence of metronidazole and tinidazole on the usefulness of guar gum, a colon-specific drug carrier based on the metabolic activity of colonic bacteria, using matrix tablets of albendazole containing 20 of guar gum as a model formulation.

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Albendazole is an anthelmintic an-thel-min-tik or anti-worm medication.

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Of these, further analysis was performed on mbz and albendazole because, in the words of the authors, they are registered pharmaceuticals for clinical use in humans, thus easily accessible for clinical testing.