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A multi-center, prospective, open-label, randomized, active-controlled trial compared the effectiveness of 12 weekly doses of priftin in combination with isoniazid 3rpt inh arm administered by directly observed therapy to 9 months of self-administered daily isoniazid 9inh arm .
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For following patient compliance the potts-cozart test 9 , a simple colorimetric 6 method of checking for isoniazid in the urine, is a useful tool for assuring patient compliance, which is essential for effective tuberculosis control.
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However, the use of isoniazid is recommended for those with the additional risk factors listed above 1 to 6 and on an individual basis in situations where there is likelihood of serious consequences to contacts who may become infected.
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