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this type of administration has been shown to provide adequate delivery of minocycline to the brain across the blood brain barrier as assessed by both serum and csf levels 20 .
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contrary to their hypothesis, researchers discovered that mice treated with minocycline exhibited no antidepressant or anxiolytic behavioral changes compared to mice receiving imipramine a tricyclic antidepressant or diazepam a benzodiazepine anxiolytic .
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if you are taking medicines containing any of the following ingredients they should be taken at least three hours before or after your minocycline dose .
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