The mutated protein, but not the wild-type transporter, transports chloroquine when expressed in xenopus oocytes and is thought to mediate chloroquine leak from its site of action in the digestive vacuole 13 .
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plaquenil is an oral medicinal drug that is made up of hydroxychloroquine sulfate, which is a colourless, crystalline solid that is partly water soluble.
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these drugs have the potential chloroquine has been used in the treatment of rheuma- excluding any drug resistance for effecting a clinical toid arthritis and lupus erythematosus see chapter 36 , cure; that is, they can reduce the parasitemia to zero.
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