Analysis of dose effect functions revealed a significant positive correlation between ethanol intake and increases in accumbal extracellular dopamine levels in saline-treated controls but not in naltrexone-treated rats.
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the interaction is expressed in terms of declining hazard ratios with increasing vs cue reactivity, the risk of relapse decreased in patients assigned to naltrexone compared to those treated with acamprosate.
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according to a study published in journal of clinical pyschopharmacology , although both groups showed decreases in smoking urge scores through treatment, the reductions were larger in the naltrexone group, with an average brief questionnaire of smoking urge scale score decrease of 13.
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