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the replacement of lysine with threonine at position 76 k76t is necessary for the observation of in vitro chloroquine resistance 5 , 6 .
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a long-established antibiotic, doxycycline, used to treat acne, has also been shown to be effective against chloroquine-resistant malaria, although it is not licensed for this use.
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We believe that our results, besides shedding light on the mechanism of chloroquine resistance in p.
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