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The risk of dose-related toxicity increases when peak chloramphenicol base serum concentrations persistently exceed 25 mg l.
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18 it is possible the chloramphenicol would produce similar synergism with other antibiotics which act by inhibiting protein synthesis.
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In an era of increasing resistance to many antibacterial agents, chloramphenicol might have an important role in the treatment of intra abdominal infections and respiratory tract infections caused by multi drug-resistant pathogens.
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chloramphenicol is a broad-spectrum antibiotic used for the treatment of many bacterial infections.