Lioresal depresses monosynaptic and polysynaptic reflex transmission, probably by stimulating the gaba b receptors, this stimulation in turn inhibiting the release of the excitatory amino acids glutamate and aspartate.
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anxiety and confusional state, delirium, hallucination, psychotic disorder, mania or paranoia, convulsion status epilepticus , dyskinesia, tachycardia, hyperthermia, rhabdomyolysis and temporary aggravation of spasticity have been reported with abrupt withdrawal of lioresal, especially after long term medication.
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chemically, generic lioresal baclofen is related to gamma-aminobutyric acid gaba which is a naturally-occurring neurotransmitter in the brain, that is, a chemical that nerves use to communicate with one another.
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Description lioresal baclofen is a muscle relaxant used to treat muscle spasms associated with multiple sclerosis or spinal cord injuries.
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