A double-blind study of paroxetine, fluoxetine, and placebo in outpatients with major depression – editor in this 8-week study, there was no difference in effectiveness between paroxetine, fluoxetine and placebo.
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while patients may notice improvement with treatment with paroxetine hydrochloride in 1 to 4 weeks, they should be advised to continue therapy as directed.
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total length of treatment with paroxetine was 12 weeks.
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mirtazapine has faster onset of overall therapeutic efficacy than paroxetine.
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as with other selective 5-ht uptake inhibitors, paroxetine causes symptoms of excessive 5-ht receptor stimulation when administered to animals previously given monoamine oxidase mao inhibitors or tryptophan.
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Paroxetine is used to treat depression, obsessive-compulsive disorders, panic attacks, social anxiety disorder, generalized anxiety disorder, and posttraumatic stress disorder.
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