The dosage of methotrexate prescribed to each patient will vary.
Men and woman should use birth control to prevent pregnancy while on the medication as methotrexate use by either partner may cause birth defect.
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Therefore,patients receiving concomitant therapy with methotrexate and otherpotential hepatotoxins e.
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Hepatotoxicity liver injury has not been significant if patients with pre-existing liver disease, alcohol abuse, or hepatic dysfunction are excluded from treatment with methotrexate.
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even a low dose of methotrexate can also help to prevent the immune system from creating antibodies to the biologic, which make it become ineffective.
