For people taking vytorin, liver problems that may develop include hepatitis, cirrhosis and even liver failure.

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because of an increased risk for myopathy in chinese patients taking simvastatin 40 mg coadministered with lipid-modifying doses greater than or equal to 1 g day niacin of niacin-containing products, caution should be used when treating chinese patients with vytorin doses exceeding 10 20 mg day coadministered with lipid-modifying doses greater than or equal to 1 g day niacin of niacin-containing products.